Lifestyle

Targeted drug shows activity against brain metastases in kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need. The drug, cabozantinib, is a tyrosine kinase inhibitor that attacks several targets in cancer cells. […]

Lifestyle

Stem cell study: Cystic fibrosis patients may see personalized treatments emerge from drug screening in a dish

Stem cell researchers may soon have a new way to identify and develop novel, personalized therapies for patients with Cystic Fibrosis (CF) who lack effective treatments. Currently, not all CF patients have access to effective treatments, especially those with very rare CF-causing mutations. To identify new therapies for these people, precursor lung cells (cells not […]

Lifestyle

Lab-grown ‘mini brains’ hint at potential treatment options for motor neurone disease and frontotemporal dementia

Cambridge researchers have developed ‘mini brains’ that allow them to study a fatal and untreatable neurological disorder causing paralysis and dementia—and for the first time have been able to grow these for almost a year. A common form of motor neurone disease, amyotrophic lateral sclerosis, often overlaps with frontotemporal dementia (ALS/FTD) and can affect younger […]

Lifestyle

New report demands action to address mental health inequalities faced by deaf community

Deaf people in Wales are experiencing significant mental health inequalities because there is a lack of accessible services, no specialist Deaf mental health service in Wales and limited training about Deaf issues for health and care workers, according to a new report. “Deaf People Wales: Hidden Inequality” highlights the challenges faced by Deaf people in […]

Lifestyle

Nontoxic drug delivery system could lead to effective therapies for currently untreatable cancers

A non-toxic, bacteria-based system developed at the University of Massachusetts Amherst can detect when it is inside a cancer cell and then release its payload of therapeutic drugs directly into the cell. The work, published in Nature Communications today, could lead to effective, targeted therapies for currently untreatable cancers, such as liver or metastatic breast […]

Lifestyle

Promising opportunities for treating skin fibrosis

Collagen, the main component of the skin’s extracellular matrix, can cause a pathological condition if it is in excess. Applying an electric field to the skin affects collagen pathways, temporarily reducing collagen production and increasing its degradation. This is what researchers from the CNRS, Université Toulouse III—Paul Sabatier and Toulouse INP have just demonstrated, along […]

Lifestyle

Breast milk companies are popping up around the globe: Why haven’t governments stepped in?

Over the last few decades, the demand for breast milk has grown. The message “breast is best” has driven parents and caregivers to buy breast milk. Even the unwell, bodybuilders and “clean eaters” are known to use it. Once limited to milk banks and peer-to-peer sharing, a new for-profit milk market has emerged. Companies producing […]